Allopurinol .. mode of action
“…RECENT FINDINGS: The first quality indicatorsfor gout management have been proposed. SelectiveCOX II inhibitors, as well as traditional NSAIDs,are effective in acute gout. A new xanthineoxidase inhibitor, febuxostat, and pegylateduricases are in clinical trials. SUMMARY: Thetherapeutic aims in gout include termination ofthe acute attack as promptly and gently aspossible, prevention of future attacks,prevention or reversal of complications of the,and prevention or reversal of associated featuressuch as obesity, hypertriglyceridemia,hypertension, or alcoholism.”
I know allopurinol happens to interfere withxanthine oxidase but is this its primary mode ofaction? Would xanthine oxidase disruption belikely to affect a fungus?