Comments on: Minor side effects of allop

By: Shira Colon

Shira Colon — Mon, 23 Jul 2007 19:26:57 +0000

Although I have no significant advice or help for your situation (justan average Joe hehe) I wanted to ask you why you are taking so muchcolchicine? Are you not running to the bathroom constantly other thento pee? I wont bring up the stomach cramps but I’m sure you know whatI mean if you have taken colchicine before. Anyway, what I wasgetting to is that your body maybe getting drained of vital nutrientsbecause they might be going in one end and right out the other. Just athought. I don’t know what your diet consist of, as far as making sureyou get enough potassium etc for those muscle cramps/spasms. I don’tknow if this even is related in anyway to what you are going thru butI’m sure we will get some feedback/insight from our resident expertsArnold and Walter.

Possibly another way to conduct a test on yourself would be to loweryour dosage of allopurinol to 200mg(if they make that strength, onlyseen it in 100 & 300) or 100mg for a while to build up to the 300mg.

Not to bore you with my all too common story but when I was firstdiagnosed with gout or should say first started takingallopurinol(different time frames) I started with 100mg, just didn’ttake it regularly so I had somewhat of a buildup phase. Since I’vebeen on the 300mg daily, bout 8 months now if I’m guessing right, Ihave not taken any colchicine or anything else related for that matter.

By: Sabina Shamel

Sabina Shamel — Tue, 24 Jul 2007 02:42:54 +0000

If you are on allopurinol you should take culcchine and nsaid’s if,and only if, you are in the middle of a gout attack. If your gout hassubsided, even if it is still twinging but clearly going away, stopthe culcchine.

Absolutely stop taking it.

The culcchine should only be used as a last resort when the NSAID youtake has failed to stem the tide of a gout attack and the pain isincreasing.

I repeat, do not take any culcchine at all, ever, unless you areunder attack from gout.

It should not be used as a daily dose to keep the gout monster away.That is stupid medical practice and I will challenge any physician,anywhere, who says different. In my opinion, there is sufficientinformation available from the long term deliterious effects ofculcchine, taken every day, to allow for legal action for those whostill perscribe it as a daily suppliment rather than perscribingallopurinol. In my opinion it amounts to malpractice.

Culcchine is a very dangerous drug. Just because you do not sufferfrom the usual problems that people usually have with culcchine doesnot, in any way, suggest that you are not being dammaged just as muchas anyone else. In fact, if you do not react to it I would think thatit is more dangerous to you because your body does not know that itneeds to react to the poison.

If you happen to be someone who cannot take allopurinol and you haveto rely on culcchine then by all means you have to do what you haveto do but for those on allopurinol, culcchine should only be used ifyou are under attack from gout.

Do you knoe what the main use of culcchine is?

It is used to induce mutations in biology and botany labs.It makes mutations happen. It is one of the most effective mutagensknown and it is dangerous to take too much of it. I don’t want toscare you off but at the same time understand what it is need forwith gout. It is there for you to stop gout from progressing but itis not something to take every day when you are not having a goutattack.

By: Columbus Luthe

Columbus Luthe — Tue, 24 Jul 2007 15:06:44 +0000

I had similar problems, though the leg pain was accompanied by extreme fatigue.Â I was on three colchicine per day as well, and it caused me to become quite anemic.Â It was probably a combination of cutting the foods from my diet that were richest in iron (because they happened to be gout triggers) and the actions of the colchicine (most notably chronic diarrhea).Â I started taking an iron supplement, and in a few days I was fine.

By: Shira Colon

Shira Colon — Wed, 25 Jul 2007 06:21:54 +0000

hat is very interesting.Â I felt sure that I could not have been the only one. Â I might try cutting down on this Colchicine now since I have rather come to the end of my experimentation.

By: Terrance Molock

Terrance Molock — Thu, 26 Jul 2007 00:25:38 +0000

The fatigue..i/e muscle weakness/pain? issue is a HIGHLY complexone. Uric acid is good!..AND the bodies regulatory mechanism keeps itin check..and it’s balance.Between the amount produced during cellbreakdown/the amount produced during food metabolisation..THEN theamount regulated for disposal.PROBLEM for gout sufferers is the bodyin gout sufferers allows too much into the joint area..this is simplyunknown how/why.Uric acid is a scavenger..traveling in the clear(plasma) part of the blood..picking up waste,free radicals otherstuff for disposal.Even at the VERY last stage of disposal the bodysays HEY! wait a minute..don’t throw that out..and some uric acid isreclaimed..no known explanation for this.

The general cause of muscle soreness,exhaustion is the lactic acidbuild up..and the bodies inability to deal with it fast enough.

The body ALWAYS deals with lactic acid FIRST!..THEN uricacid..again this is unknown why.

I think that the allopurinol affecting the bodies own productionof uric acid..yes..really throws things out of wack for a while..

Whether at the time there is insufficient uric acid for cleanup..OR that the extra uric acid is somehow needed? to help clear outthe lactic acid..I do not know.