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	<title>Comments on: Allopurinol works</title>
	<link>http://www.goutdietblog.com/archives/99</link>
	<description>Diet for gout</description>
	<pubDate>Tue, 06 Jan 2009 11:30:14 +0000</pubDate>
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		<title>By: Sabina Shamel</title>
		<link>http://www.goutdietblog.com/archives/99#comment-247</link>
		<author>Sabina Shamel</author>
		<pubDate>Sun, 27 May 2007 08:19:12 +0000</pubDate>
		<guid>http://www.goutdietblog.com/archives/99#comment-247</guid>
					<description>No one would mistake you for one either.

Suggest one alternative please.

Not angry, not intolerant abut 100% accurate. If I thought you wouldread it I would provide the detailed chemitry analysis that provesit, the extensive double blind test groups and the absolutelyunquestioned statistical information that proves, beyond any marginfor error, that allopurinol works, how it works and that unless youare either not a mammal-for it works on all mammals-dogs, rats,horses-yes horses get gout too- or perhaps if you are not human  andhave a different biological evolution it might not work on you but inall human cases testedn it absolutely stops, inhibits, makes go away,the breakdown process that leads to uric acid.

Maybe you should learn to read, Never said that, I said that peoplewith serum urate levels as low as 4 can suffer from gout.Do you even know the difference between the level of uric acid youhave in your body and the level of urate you have in your blood. Arethey the same thing. Have you eveh had your body level of uric acidmeasured. Do you konw what that level is?

all

Yes we are all the same in the major metabolic pathways.

bethere

The chemical that we call allopurinol does not occur naturally. It isa homolog of many other chemicals that do occur naturally.

I challenge you to find one message in which I wrote that you arean "ignorant idiot".If you wish to proclaim to the world that you are, an "ignorantidiot" that is your privledge. I do claim that based on yourstatements, you are very ignorant about the biochemistry ofmetabolism, specifically the breakdown of DNA and RNA into uric acidand morespecifically what allopurinol does and why it helps us dealwith our damaged systems.

If memory serves me you have an autistic daughter and you and otherpeople close toyou are suggesting that perhaps heavy metalcontamination plays a role in the condition. I neither argued withyou nor do I believe that the argument or discussion is withoutmerit. My sister believes that her daughter, who also suffers from aform of autism caused by a near drowning when she was three, is alsoterribly sensitive to the mercury amalgam that she has in her teethand my sisteh has had all the amalgam fillings removed. She and mymom both believe that there has been a marked improvement in hercognitive ability since the fillings were replaced with the porcelainpaste fillings.

Really hard to do since I am almost completely bald but I guess Icould get it done on my hair on my arm. Sop what if I do have otherissues. None of the other issues that could be going on with me countwhen I am in the middle of a rip snorting gout attack that makes myfoot twice the size it was the previous day. I really don't care whymy gout got here. I do know that I have many relatives who are olderthan me and who have suffered many many years with gout and in alllikelyhood there will be a brilliant discovery some day that willallow many of us to go off allopurinol.

But that day ain't here now and neither you, nor anyone else outthere, can produce credible information that shows there is analternative.

What is it? What is the alternative and where can I read about it?How does it work and why?

The lady who discovered and in fact pioneered the use of allpurinolwasn't even looking for a cure for gout.  She was trying to find away to mitigate the terrible overload of uric acid that cancerpatients get when radiation therapy destroyes a large mass of atumor. We should actually name this group after her and by the way,she won the Nobel prize for that work and she was not working for adrug company when she did it. If you would spend 1/4 of the energyyou spend fretting about statements that I have made and use thatenergy to read what is in the literature about allopurinol, you mightmitigate your anger. Do you konw why allopurinol is so cheap, that islow in cost? Interesting story. And by the way, the drug companiesactually don't, didn't want to produce it because they didn't havethe patent rights to it.

Get your facts strait and perhaps get your temper and outlookrealigned. I really don't care, as you suggest, whether you ever takeallopurinol or not. I do care about things that you write that areclearly wrong and that can and probably do influence peopleimproperly.

inhibit

Again you are showing a terribly naieve lack of understanding of theprocesses that are involved in uric acid retention and excretion.

(I really don't think you are someone who has gout. )

We are making the source of the problem go away and no one is healedfrom allopurinol, they are just allowed to reduce their excess uricacid, gradually over several years without having to suffer theravages of severe gout attacks.

My guess, from what you write, is that you really don't have gout,never have and don't even know from personal experience, just howpainful it is and how debilitating and damaging it is. It will robyou of your mobility, your self respect and in all to many cases itcan and will ruin your life. You will in all likelyhood lose yourjob,  the love of your family, and your own sense that you are animportant and worthwhile person because with constant gout attacks,even a saint, is reduced to something less than human.

Go and find us a better way but please, when you do find it, andbring it to us, try to have some specifics on what that better way isand, it might help to suggest why you believe it works. Some of usare data driven and you don't present much data.</description>
		<content:encoded><![CDATA[<p>No one would mistake you for one either.</p>
<p>Suggest one alternative please.</p>
<p>Not angry, not intolerant abut 100% accurate. If I thought you wouldread it I would provide the detailed chemitry analysis that provesit, the extensive double blind test groups and the absolutelyunquestioned statistical information that proves, beyond any marginfor error, that allopurinol works, how it works and that unless youare either not a mammal-for it works on all mammals-dogs, rats,horses-yes horses get gout too- or perhaps if you are not human  andhave a different biological evolution it might not work on you but inall human cases testedn it absolutely stops, inhibits, makes go away,the breakdown process that leads to uric acid.</p>
<p>Maybe you should learn to read, Never said that, I said that peoplewith serum urate levels as low as 4 can suffer from gout.Do you even know the difference between the level of uric acid youhave in your body and the level of urate you have in your blood. Arethey the same thing. Have you eveh had your body level of uric acidmeasured. Do you konw what that level is?</p>
<p>all</p>
<p>Yes we are all the same in the major metabolic pathways.</p>
<p>bethere</p>
<p>The chemical that we call allopurinol does not occur naturally. It isa homolog of many other chemicals that do occur naturally.</p>
<p>I challenge you to find one message in which I wrote that you arean &#8220;ignorant idiot&#8221;.If you wish to proclaim to the world that you are, an &#8220;ignorantidiot&#8221; that is your privledge. I do claim that based on yourstatements, you are very ignorant about the biochemistry ofmetabolism, specifically the breakdown of DNA and RNA into uric acidand morespecifically what allopurinol does and why it helps us dealwith our damaged systems.</p>
<p>If memory serves me you have an autistic daughter and you and otherpeople close toyou are suggesting that perhaps heavy metalcontamination plays a role in the condition. I neither argued withyou nor do I believe that the argument or discussion is withoutmerit. My sister believes that her daughter, who also suffers from aform of autism caused by a near drowning when she was three, is alsoterribly sensitive to the mercury amalgam that she has in her teethand my sisteh has had all the amalgam fillings removed. She and mymom both believe that there has been a marked improvement in hercognitive ability since the fillings were replaced with the porcelainpaste fillings.</p>
<p>Really hard to do since I am almost completely bald but I guess Icould get it done on my hair on my arm. Sop what if I do have otherissues. None of the other issues that could be going on with me countwhen I am in the middle of a rip snorting gout attack that makes myfoot twice the size it was the previous day. I really don&#8217;t care whymy gout got here. I do know that I have many relatives who are olderthan me and who have suffered many many years with gout and in alllikelyhood there will be a brilliant discovery some day that willallow many of us to go off allopurinol.</p>
<p>But that day ain&#8217;t here now and neither you, nor anyone else outthere, can produce credible information that shows there is analternative.</p>
<p>What is it? What is the alternative and where can I read about it?How does it work and why?</p>
<p>The lady who discovered and in fact pioneered the use of allpurinolwasn&#8217;t even looking for a cure for gout.  She was trying to find away to mitigate the terrible overload of uric acid that cancerpatients get when radiation therapy destroyes a large mass of atumor. We should actually name this group after her and by the way,she won the Nobel prize for that work and she was not working for adrug company when she did it. If you would spend 1/4 of the energyyou spend fretting about statements that I have made and use thatenergy to read what is in the literature about allopurinol, you mightmitigate your anger. Do you konw why allopurinol is so cheap, that islow in cost? Interesting story. And by the way, the drug companiesactually don&#8217;t, didn&#8217;t want to produce it because they didn&#8217;t havethe patent rights to it.</p>
<p>Get your facts strait and perhaps get your temper and outlookrealigned. I really don&#8217;t care, as you suggest, whether you ever takeallopurinol or not. I do care about things that you write that areclearly wrong and that can and probably do influence peopleimproperly.</p>
<p>inhibit</p>
<p>Again you are showing a terribly naieve lack of understanding of theprocesses that are involved in uric acid retention and excretion.</p>
<p>(I really don&#8217;t think you are someone who has gout. )</p>
<p>We are making the source of the problem go away and no one is healedfrom allopurinol, they are just allowed to reduce their excess uricacid, gradually over several years without having to suffer theravages of severe gout attacks.</p>
<p>My guess, from what you write, is that you really don&#8217;t have gout,never have and don&#8217;t even know from personal experience, just howpainful it is and how debilitating and damaging it is. It will robyou of your mobility, your self respect and in all to many cases itcan and will ruin your life. You will in all likelyhood lose yourjob,  the love of your family, and your own sense that you are animportant and worthwhile person because with constant gout attacks,even a saint, is reduced to something less than human.</p>
<p>Go and find us a better way but please, when you do find it, andbring it to us, try to have some specifics on what that better way isand, it might help to suggest why you believe it works. Some of usare data driven and you don&#8217;t present much data.</p>
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